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Medium star Patricia Arquette (the above mentioned sister to Jennifer Aniston's best friend's husband) has filed for divorce from her husband of two years, actor Thomas Jane.

TMZ reports that Arquette filed the paperwork citing that old standby, "irreconcilable differences."

Pat and Jane are parents to five-year-old daughter Harlow Olivia Calliope (and we thought Nicole was so original!)

Apparently Patricia has retained the services of Britney's former attorney, Laura Wasser, so she should be protected even though she's got no pre-nup!