Johnny Depp is keeping it all in the family!

The Oscar winner is set will to co-star with his 15-year-old daughter Lily-Rose in the upcoming Kevin Smith film Yoga Hosers, People reports. The comedy-action movie, which features Justin Long, Adam Brody, Tyler Posey and Natasha Lyonne, will be quite the family affair -- in addition to Depp's offspring, Smith's 15-year-old daughter Harley Quinn nabbed the other lead role.

In the film, Lily-Rose and Harley Quinn play bored, yoga-loving convenience store clerks who most go against manhunter Guy Lapointe (played by Depp).

Smith has said he is often asked whether or not he will make a comic book movie -- and this film is his answer to that -- honoring his love of comic books and the strength of teenage girls.

"This is it but instead of yet another dude saving the day, our antiheroes are the most feared and formidable creatures man has ever encountered: two 15-year-old girls."

The movie, which begins filming this week, is the second installment in Smith's True North Trilogy -- and is the follow-up to Tusk.