Williams+Hirakawa for Variety

It's all about girl power, baby! Jennifer Lopez and Reese Witherspoon are just two of the famous ladies being honored in Variety's sixth annual Power of Women issue.

Three other powerful women, Viola Davis, Jane Fonda and Donna Langley, are the other women who are gracing the five separate covers for mag's celebration of women. The iconic Hollywood magazine is paying tribute to the celebrities who are using their star status to advocate for women's causes.

Reese has used her stardom to shed light on other worthy causes on education for young girls through the Malala Fund, after her 15-year-old daughter brought the story of Malala Yousafzai, A Pakastani girl who was shot by the Taliban for fighting for the right to an education, to her attention.

"It's incomprehensible to me sometimes how few opportunities women have in some areas," the Oscar winner said after she heard Malala's incredible story.

Similarly, JLo has been championing health management with her Lopez Family Foundation, which she founded in 2009.

Along with her sister Lynda, the women have worked with a multitude of medical facilities in Los Angeles, Brooklyn, Panama and Puerto Rico to help fund the medical costs of those without financial resources.