Jennifer Aniston celebrated her 50th birthday Saturday night and her exes came out of the woodwork!

The Friends star went to her favorite supper club at Sunset Tower in West Hollywood to fete ... herself! Pals like George and Amal Clooney, Gwyneth Paltrow, Katy Perry and Orlando Bloom, Reese Witherspoon, Jon Hamm, Kate Hudson, John Mayer and Brad Pitt all turned out for the bash!

The star-studded event was missing one of Aniston's significant others -- ex-hubby Justin Theroux. As was recently reported, the former husband and wife have "no contact" and made a "clean break" after their February 2018 divorce, only three years into their marriage.

Chelsea Handler, Ellen DeGeneres, Courteney Cox and her ex-hubby David Arquette, Robert Downey, Jr., David Spade, Pharrell, Diane Keaton, Barbra Streisand -- this was an A-list HEAVEN!